Mouse anti‑Human CD34 IgG1,k Monoclonal RW-C389524-100

Antibody: CD34 Mouse anti-Human Monoclonal (N-Terminus) (Azide-free, BSA-free) (QBEnd/10) Antibody, Application: IHC, IHC-P, IF, WB, IP, Flo, Reactivity: Human, Cynomolgus monkey, Rhesus monkey, Format: Unconjugated, Azide-free, BSA-free, Other formats: Ready-to-Use Unmodified, Descriptio: CD34 antibody RW-C389524 is an unconjugated mouse monoclonal antibody to CD34 (N-Terminus) from human. It is reactive with human, cynomolgus monkey and rhesus monkey. Validated for Flow, IF, IHC, IP and WB., Targe: Human CD34, Synonym: CD34 | CD34 molecule | CD34 antigen | HPCA1, Hos: Mouse, Reactivit: Human, Cynomolgus monkey, Rhesus monkey (tested or 100% immunogen sequence identity), Non-Reactivit: Rat, Bovine, Dog, Sheep, Clonalit: IgG1,k Monoclonal, Clon: QBEnd/10, Conjugation: Unconjugated, Purificatio: Protein G purified, Modification: Azide-free, BSA-free. Also available Unmodified or Ready-to-Use., Immunoge: A detergent solubilized vesicular suspension prepared from human term placenta., Epitop: N-Terminus, Specificit: Human CD34, Application: IHC
IHC - Paraffin (0.5 - 1 µg/ml)
Immunofluorescence (0.5 - 1 µg/ml)
Western blot
Immunoprecipitation
Flow Cytometry (0.5 - 1 µg/10E6 cells), Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more: None, Usag: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into three main categories, class I, class II and class III. This is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. CD34 antibody labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity., Presentatio: 1X PBS, Storag: Store at 2°C to 8°C., Restriction: For research use only. Intended for use by laboratory professionals., Guarante: This antibody carries the RW 100% Guarantee., About CD3: Uniprot: P28906 NCBI: NM_001773 NP_001764.1